| Edit |   |
|---|
| Antigenic Specificity | Human HRI |
|---|
| Clone | 8I4M4 |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG |
|---|
| Format | unconjugated |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit Anti-Human HRI monoclonal antibody for WB. The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme. |
|---|
| Immunogen | Protein corresponding to human elF2AK1 / Heme regulated inhibitor (HRI) (aa271-630) |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 27102, UniProt: Q9BQI3 |
|---|
| Catalog # | DCABH-4267 |
|---|
| Price | |
|---|
| Order / More Info | Human HRI Antibody from CREATIVE DIAGNOSTICS |
|---|
| Product Specific References | n/a |
|---|