A vitamin B6 antimetabolite; inhibits transport of pyridoxine, pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells; inhibits S1P lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells; decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy; reduces TNF-α and IL-6 production in mice infected with T. spiralis,