Corazonin is a highly conserved neuropeptide hormone from insects, having cardioacceleratory function. Corazonin (from corazon, Spanish for heart) is produced by lateral brain neurosecretory cells projecting to the corpora cardiaca-corpora allata complex and in neurons of the ventral nerve cord. This new cardioaccelerating peptide isolated from the corpus cardiacum of the American cockroach, Periplaneta americana, is the most potent insect cardioactive neuropeptide.