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Description
Rat Anti-Mouse CASP12 monoclonal antibody for WB, ELISA, IHC, IP. Caspase 12, an enzyme encoded by the CASP12 gene, is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases is critical for cell apoptosis. Once a stimulus is received by the cell, discrete apoptotic pathways are potentiated by subsets of the caspases that can then activate additional intracellular effectors. Caspase 12 is involved in apoptosis induced by ER stress.