If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
APG5L Polyclonal Antibody. ? Target Background: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. The ATG12
Immunogen
KLH conjugated synthetic peptide derived from human APG5L. Immunogen Range: 118-158/275
Song, F. et al. (2013) Neurochem Int. 2013 Nov 9. PubMed: 24220541 // Lang, Fangfang, et al. (2015) PLoS ONE 10.6:e0129196. PubMed: 26067645 // Tang, Qishan, et al. (2013) Cancer Lett. 336.2:325-337. PubMed: 23541682 // Tang, Qishan, et al. (2013) Cancer Lett. 336.2:325-337. PubMed: 23541682 // Li, Yue, et al.(2017) Toxicol Appl Pharmacol. PubMed: 28130038 // Zhang et al. (2015) Oncotarge. 6:789-801. PubMed: 25596736