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Description
Rabbit Anti-Human AGTRAP polyclonal antibody for WB, IHC. Type-1 angiotensin II receptor-associated protein, also known as, AT1 receptor-associated protein, and encoded by the gene name(s), AGTRAP or ATRAP, appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. AGTRAP is present in perinuclear vesicular membranes, endoplasmic reticulum, Golgi and endocytic vesicles. It is ubiquitously expressed; however, it is more abundant in kidney, heart, pancreas and thyroid.