If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Mouse Anti-ABCA4 Recombinant Antibody (3F4). This product is a mouse antibody that recognizes ABCA4 of bovine. The antibody 3F4 can be used for immunoassay techniques such as: WB, IHC. In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. The protein may play a role in photoresponse, removing ATR/NR-PE fr
Immunogen
Partially purified bovine 220-kDa disc rim protein
Other Names
retinal-specific ATP-binding cassette transporter; ATP-binding cassette, sub-family A (ABC1), member 4