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| Antigenic Specificity | GAD65 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:32000, Western Blot: 0.5-1.5 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GAD65 Polyclonal Antibody. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
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| Immunogen | n/a |
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| Other Names | GAD2; GAD65; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); RP11-420F12.2; MGC161605; MGC161607; Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 2 |
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| Gene, Accession # | Entrez: 2572; Uniprot: Q05329 |
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| Catalog # | PA5-18369 |
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| Price | |
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| Order / More Info | GAD65 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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