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Description
Mouse Anti-DKK3 Recombinant Antibody (8A5C6). Provided herein is a Mouse monoclonal antibody, which binds to Dickkopf WNT Signaling Pathway Inhibitor 3 (DKK3). The antibody can be used for immunoassay techniques, such as ELISA, FC, IHC, IHC-P, WB. DKK3 is a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Immunogen
The immunogen corresponding to a region within amino acids 91 and 350 of human DKK3 expressed in E. Coli