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Description
Rabbit IgG polyclonal Picoband? antibody for ROBO1 detection. Tested with WB, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Roundabout homolog 1 is a protein that in humans is encoded by the ROBO1 gene. Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
E.coli-derived human ROBO1 recombinant protein (Position: F264-P897).
Other Names
Roundabout homolog 1; Deleted in U twenty twenty; H-Robo-1; ROBO1; DUTT1