Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) protein
Description
Latent recombinant human pro-collagenase (MMP-13) also called collagenase-3 truncated from C-terminal.Matrix Metalloproteinase-13 (MMP-13) is an enzyme that is a member of the MMP extracellular protease family. Extracellular protease enzymes, by virtue of their broad substrate specificities1, play a role in both normal and disease states of tissue proliferation. Among the targets of MMP-13 are collagen, gelatin, entactin, pro-TNF-a, and chemokine SDF-11-4.MMP-13 is found in its latent form as a 52-56 kDa glycosylated proenzyme. Upon cleavage the 22-46 kDa5 MMP-1 becomes active in extracellular matrix remodeling.Because of the prominent role that MMP-1 plays in cell migration and metastasis, it is an important target for inhibition screening Synonyms: Collagenase 3, EC 3.4.24.-, Matrix metalloproteinase-13, MMP-13, CLG3
Size
10 μg
Concentration
n/a
Applications
n/a
Other Names
cb1034|mmp13|MMP13|xCol|xcl3|MMP-13|MGC108008|Clg|Mmp1|CLG3|MANDP1|gene A