Microtubule-Associated Protein tau (MAPT) (AA 1-352) protein (His tag)
Description
MAPT is a neuronal microtubule associated protein localized mostly on axons. MAPT promotes tubulin polymerisation and stabilizes microtubules, however it also serves to connect certain signalling pathways to the cytoskeleton. MAPT, in its hyperphosphorylated form, is the main part of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimers disease (AD) brain Synonyms: TAU, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND