Purity: > 95% by SDS - PAGE Format: In 20mM Tris-HCl (pH8.0) buffer containing 30% glycerol . Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. GRB2 is widely expressed and also binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Grb2 is composed of an SH2 domain flanked on each side by an SH3 domain. Inhibition of Grb2 function impairs developmental processes in various organisms and blocks transformation and proliferation of various cell types. Recombinant human GRB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2.