Purity: > 90% by SDS - PAGE Format: Liquid. In PBS (pH 7.4) containing 2mM DTT, 30% glycerol, 200mM NaCl . EXOSC5, also known as exosome component 5, belongs to the RNase PH family. EXOSC5 has been shown to interact with Exosome component 8 and Exosome component 1. It is Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. It highly expressed in a variety of hematopoietic and epithelial tumor cell lines, but not in normal hematopoietic tissues or other normal tissue, with the exception of testis. Recombinant human EXOSC5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.