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| Antigenic Specificity | SHC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor? 488 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SHC Polyclonal Antibody, Alexa Fluor? 488 Conjugated. ? Target Background: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-ne |
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| Immunogen | KLH conjugated synthetic peptide derived from human SHC. Immunogen Range: 480-520/583 |
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| Other Names | SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1; SHC1 |
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| Gene, Accession # | Gene ID: 6464, SwissProt: P29353 |
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| Catalog # | bs-3572R-A488 |
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| Price | |
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| Order / More Info | SHC Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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