Kallikrein-14 is a protein that in humans is encoded by the KLK14 gene. Kallikrein-14 belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. Kallikrein-14 gene is identified in the kallikrein gene cluster on chromosome 19q13.4. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. Kallikrein-14 may activate or inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. Sample Type: Cell culture supernates, cell lysates, serum, plasma (heparin, EDTA) and tissue homogenates Intended Use: For quantitative detection of human Kallikrein 14 in cell culture supernates, cell lysates, serum, plasma (heparin, EDTA) and tissue homogenates. Sensitivity: <2pg/ml Range: 15.6-1000pg/