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Description
Mouse Anti-LITAF Recombinant Antibody (CBYCL-358). Provided herein is a Mouse monoclonal antibody against Human LITAF. The antibody can be used for immunoassay techniques, such as ELISA, WB. Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C
Immunogen
Recombinant human LITAF amino acids 1-161 purified from E.coli