Alpha-galactosidase A, Recombinant, Human, aa32-429, His-Tag (GLA, GALA)
Description
Purity ~90% (SDS-PAGE). GLA, also known as alpha-galactosidase A, is homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Source: Recombinant protein corresponding to aa32-429 from human GLA, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~46.4kD (406aa) AA