Purity >98% by HPLC. An ATP-competitive pan-Akt kinase inhibitor. Inhibits Akt kinase isoforms 1, 2, 3 with IC50 values of 2, 13, and 9 nM, respectively. Inhibited proliferation and induced apoptosis in a subset of tumor cells with potency consistent with intracellular inhibition of Akt kinase activity.