Recombinant Human FGF-7 / Glrb Protein (Animal Free)
Description
Purity >90 as determined by SDS-PAGE. Fibroblast growth factor 7 (FGF7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb). The mitogenic activity of FGF7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF7 expression is upregulated after acute and chronic injury, suggesting that FGF7 functions during the healing of injured epithelial cells. FGF7 also induces the formation of the apical ectoderm ridge during limb development.