Activin A, Recombinant, Human (Inhibin beta-1, FRP, FSH-Releasing Protein)
Description
Purity ~95% (SDS-PAGE, HPLC). Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Source: Recombinant protein corresponding to two 117aa chains from human Activin A, expressed in E. coli. Molecular Weight: ~26.2kD Biological Activity: Determined by the ability to induce cytoxicity of MPC-11 cells and is typically <2ng/ml. Endotoxin: <0.1EU/ug purified protein AA Sequence: MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS Specificity: Human Activin A has 100% amino acid sequence identity to mouse, rat, porcine
Size
100ug
Concentration
n/a
Applications
n/a
Other Names
Inhibin beta-1, FRP, FSH-releasing protein, human recombinant Activin A, hrActivin, Activin a, recombinant activin