Purity ~95% (HPLC, SDS-PAGE). Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Rat Activin A has 100% amino acid sequence identity to human, mouse, porcine, bovine and feline proteins. Recombinant rat Activin A is a non-glycosylated homodimer, containing two 117aa chains, with a total molecular weight of 26.2kD. Source: Recombinant corresponding to rat Activin A expressed in E.coli. Molecular Weight: ~26kD Biological Activity: The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2ng/ml. Endotoxin: ~0.1EU/ug purified protein.
Size
10ug
Concentration
n/a
Applications
n/a
Other Names
Activin A, Recombinant, Rat (Inhibin beta-1, FRP, FSH-releasing protein, human recombinant Activin A, hrActivin, Activin a, recombinant activin)