JAM-A/F11R, BioAssay? ELISA Kit (Mouse) (Junctional Adhesion Molecule A)
Description
Junctional adhesion molecule A (JAM-A) is a protein that in humans is encoded by the F11R gene. It is mapped to 1q23.3. This gene is an immunoglobulin-like molecule that colocalizes with tight junctions in endothelium and epithelium and is also found on blood leukocytes and platelets. JAM-A plays an important role in the regulation of tight junction assembly in epithelia. In addition, it can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. JAM-A has a nonredundant role in controlling DC motility, trafficking to lymph nodes, and activation of specific immunity. Sample Type: Cell culture supernates, serum and plasma (heparin, EDTA) Intended Use: For quantitative detection of mouse JAM-A in cell culture supernates, serum and plasma (heparin, EDTA). Sensitivity: <10pg/ml Range: 31.2-2000pg/ml Specificity: Natural and recombinant mouse JAM-A Test Principle: This mouse JAM-A BioAssay? ELISA Kit was based on standar