Creatinine is synthesized in the body at a fairly constant rate from creatine, which is produced during muscle contractions from creatine phosphate. In the blood, creatinine is removed by filtration through the glomeruli of the kidney and is secreted into urine. In healthy individuals, creatinine secretion is independent of diet and is fairly constant. The creatinine clearance test has become one of the most sensitive tests for measuring glomerular filtration rate. In kidney disease, creatinine levels in the blood are elevated, whereas the creatinine clearance rate and hence the urine levels are diminished. Creatinine test is most widely used to assess kidney function. Sample Type: Biological samples Intended Use: Direct Assays: urine, serum, plasma and biological preparations. Drug Discovery/Pharmacology: effects of drugs on creatinine metabolism. Sensitivity: Detection limit: 0.10mg/dL (8um) Test Principle: This Creatinine BioAssay? kit is designed to measure creatinine directl