ELISA, Western Blot. Anti-DELTA-1 Antibody has been tested for use in ELISA against the immunizing peptide. It is expected that anti-Delta-1 antibody will be reactive in western blot assays Reactivity in other immunoassays is unknown.
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Description
Anti-DELTA-1 Antibody was affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. The antibody detects DELTA-1 from mouse. Activity against Delta-1 from other species has not been determined but is expected based on sequence homolgy.
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 155-173 of Mouse DELTA-1. DELTA-1 is a mouse homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Swiss Prot accession Q61483. Expected to cross-react with rat, human and chicken.
Meliou E, Kerezoudis N, Tosios K, Kiaris H. (2010) Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study). Open Dent J. 2010 Jul 27;4:153-8. doi: 10.2174/1874210601004010153.