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Description
Mouse Anti-TNFSF12 Recombinant Antibody (CBYJT-3921). Provided herein is a Mouse monoclonal antibody, which binds to TNFSF12 (TNF Superfamily Member 12). The antibody can be used for immunoassay techniques, such as WB, FC, ELISA, ICC, IF. TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TNFSF12, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis.
Immunogen
hTWEAK/2PK-3 transfectant cells
Other Names
TNF Superfamily Member 12; Tumor Necrosis Factor (Ligand) Superfamily, Member 12; APO3 Ligand; APO3L; DR3LG; TWEAK; Tumor Necrosis Factor Ligand Superfamily Member 12