Kallikrein-Related Peptidase 4 (KLK4) (C-Term), (AA 31-254) protein
Description
Recombinant Human Kallikrein 4 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (I31-S254) of Human KLK4 fused with a polyhistidine tag at the C-terminus. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.