A Factor Xa inhibitor (Ki = 0.117 nM; IC50 = 1.5 nM); selective for Factor Xa over hERG channels (Ki = 1.8 μM; IC50 = 8.9 μM); inhibits thrombin generation in a tissue factor-induced thrombin generation assay (5-25 ng/mL); inhibits thrombus mass formation 76% in a rabbit clot accretion model (3 mg/kg)