Recombinant Human C-C motif chemokine 14 protein (CCL14) (Active)
Description
Purity > 95% as determined by SDS-PAGE and HPLC. MW: 7.8kDa. Partial: 28-93aa. tag-Free. Homo sapiens (Human). Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca (2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1 (9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:11085751}.