Recombinant Human C-C motif chemokine 21 protein (CCL21) (Active)
Description
Purity > 97% as determined by SDS-PAGE and HPLC. MW: 12.2kDa. Full Length of Mature Protein: 24-134aa. tag-Free. Homo sapiens (Human). Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.