Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
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Description
GAT-1 Polyclonal Antibody. GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA ( gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha1-6, GABAA R beta1-3, GABAA R gamma1-3, GABAA R delta, GABAA R epsilon, GABAA R-rho-1 and GABAA R-rho-2. The GABAB family is composed of GABAB R1 alpha an
Immunogen
n/a
Other Names
Sodium- and chloride-dependent GABA transporter 1, GAT-1, Solute carrier family 6 member 1, SLC6A1, GABATR, GABT1, GAT1