A potent and selective CB2 receptor agonist, with 190-fold selectivity for CB2 over the CB1 receptor (Kis = 6.3 and 1,220 nM, respectively); 3 mg/kg induces analgesia in a formalin-induced nocifensive study in mice without cannabis-like behavioral effects; ameliorates insulin resistance in vivo and increases insulin secretion and accumulation in pancreatic islets isolated from HFD/STZ-induced diabetic mice