PPARγ pure antagonist with micromolar affinity in 3T3-L1 and 3T3-F442A preadipocyte cells; selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARγ. Acts as a PPARγ agonist in an ECV304 cell line. Also produces PPARγ-independent apoptosis of tumor cells via several mechanisms. Active in vivo. Purity 95%. MW (observed): 340.42
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
2,2-Bis[4-(2,3-epoxypropoxy)phenyl]propane. Bisphenol A diglycidyl ether