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Description
HOMER3 (Thr36) Polyclonal Antibody, Cy5.5 Conjugated. ? Target Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
Immunogen
KLH conjugated synthetic phosphopeptide derived from human HOMER3 around the phosphorylation site of Thr36 [AL(p-T)VS]. Immunogen Range: 32-38/361
Other Names
Phosphorylated, phospho-VESL3; HOMER-3; Homer protein homolog 3; HOMER3