產(chǎn)品名稱 GSK 2830371 from TOCRIS BIOSCIENCE
    產(chǎn)品貨號 5140/50
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 50 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
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    Product NameGSK 2830371
    DescriptionPotent and selective allosteric inhibitor of Wip1 phosphatase (IC50 = 6 nM). Exhibits selectivity for Wip1 over 21 other phosphatases. Increases phosphorylation of Wip1 substrates, including p53, Chk2, H2AX and ATM. Attenuates tumor cell growth in a variety of lymphoid cell lines. Also inhibits lymphoma xenograft growth in vivo. Potentiates growth inhibitory effects of MDM2 inhibition in cancer cell lines in a p53-dependent manner. Orally bioavailable. Purity 98%. MW (observed): 461.02
    Size50 mg
    Concentrationn/a
    Applicationsn/a
    Other Names5-[[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cycloprpylamino)-2-oxoethyl]-2-thiophenecarboxamide
    Gene, Accession, CAS #CAS: 1404456-53-6
    Catalog #5140/50
    Price
    Order / More InfoGSK 2830371 from TOCRIS BIOSCIENCE
    Product Specific Referencesn/a
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