| 產(chǎn)品詳情 |
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| Product Name | U0126 |
| Description | Potent and selective non-competitive inhibitor of MAP kinase kinase. Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 μM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4. Brain penetrant. Helps maintain human pluripotent stem cells in undifferentiated state. Available as part of the MAPK Cascade Inhibitor Tocriset? and MAPK Inhibitor Tocriset?. Negative Control also available.. MW (observed): 380.48. |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
| Gene, Accession, CAS # | CAS: 109511-58-2 |
| Catalog # | 1144/25 |
| Price | |
| Order / More Info | U0126 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 11454659, 12794003, 14749443, 15056716, 15152046, 15257286, 16086034, 16627622, 16672661, 17018141, 17160007, 17494631, 17611287, 17715342, 18295207, 18400051, 18815127, 19193899, 19276383, 19298529, 19440492, 19501068, 19547699, 19666830, 19675232, 19723763, 19788733, 19846725, 20144602, 20154358, 20412391, 20427666, 20429916, 20448669, 20471392, 20505744, 20554871, 20685979, 20855151, 21068317, 21143600, 21195749, 21228181, 21247487, 21685895, 21829588, 21859479, 21936900, 21945811, 21994479, 21995440, 22003401, 22010199, 22114332, 22129063, 22273495, 22784513, 22833676, 22922731, 22949700, 22951829, 22975404, 23071303, 23226337, 23235157, 23332156, 23339737, 23373701, 23390529, 23497702, 23518767, 23607966, 23616561, 23675235, 23699517, 23749147, 23755184, 23898828, 23950932, 24401275, 24555435, 24567337, 24684682, 24736410, 24747967, 24908484, 24977707, 25030704, 25052197, 25137150, 25263555, 25324750, 25341622, 25479176, 25479966, 25600268, 25644401, 25653381, 25712213, 25999956, 26023933, 26065826, 26100015, 26116509, 26251761, 26620707, 26733817, 26780950, 26818516, 26888925, 27089465, 27150562, 28442401, 28445734 |
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