A potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM); effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively)
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
198960-07-5 biochemical inhibitor kinase protein receptor biochemistry signal transduction cancer Pfizer compound peptide inhibit cell-permeable EGFR epidermal growth factor PD174265