Recombinant Human Tumor necrosis factor ligand superfamily member 6 (FASLG), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 21.3kDa. Extracellular Domain: 130-281aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.