bovine, canine, equine, guinea pig, human, mouse, ovine, rabbit, rat
Isotype
n/a
Format
purified
Size
100 μl
Concentration
n/a
Applications
Western Blot: 0.2-1 μg/mL
Reviews / Ratings
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Description
QPCT Polyclonal Antibody. QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86%