Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (C-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human
Isotype
n/a
Format
purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. Synonyms: Polyclonal DOK1 antibody, Anti-DOK1 antibody, docking protein 1, 62kDa, downstream of tyrosine kinase 1 antibody, MGC117395 antibody, MGC138860 antibody, P62DOK antibody.
Immunogen
DOK1 antibody was raised in rabbit using the C terminal of DOK1 as the immunogen