An α7-containing nAChR agonist; activates human α7-containing nAChRs to 60% of the levels generated by endogenous ligand acetylcholine; has no activity at α2-, α3-, and α4-containing nAChRs at a concentration of 100 μM; stimulates dopamine release from rat striatal slices (EC50 = 10 μM); decreases delay in the delayed matching-to-sample task in monkeys; suppresses amnesia and neuronal cell death in a gerbil model of ischemia-reperfusion injury