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Description
KCNMB3 Monoclonal Antibody (3E5). MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
Immunogen
n/a
Other Names
BKBETA3, HBETA3, KCNMB2, KCNMBL, SLOBETA3, BK channel subunit beta-3, K(VCA)beta-3, calcium-activated potassium channel subunit beta-3, calcium-activated potassium channel, subfamily M subunit beta-3, charybdotoxin receptor subunit beta-3, large conductance, voltage and Ca2+ activated potassium channel