Recombinant Human Cell division cycle protein 23 homolog (CDC23), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 71kDa. Partial: 14-591aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.