Recombinant Human Cell surface hyaluronidase (TMEM2), partial
Description
Purity > 85% as determined by SDS-PAGE. MW: 21.5kDa. Partial: 104-250aa. N-terminal 10xHis-tagged. Homo sapiens (Human). Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate