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| Antigenic Specificity | BTK Tyr223 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | Alexa Fluor? 555 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BTK (Tyr223) Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Btk around the phosphorylation site of Tyr223 [AL(p-Y)DY]. Immunogen Range: 190-240/659 |
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| Other Names | Phosphorylated, phospho-AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1; Tyrosine-protein kinase BTK; Agammaglobulinemia tyrosine kinase; B-cell progenitor kinase; Bruton tyrosine kinase; BTK |
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| Gene, Accession # | Gene ID: 695, SwissProt: Q06187 |
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| Catalog # | bs-3069R-A555 |
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| Price | |
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| Order / More Info | BTK Tyr223 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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