human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Isotype
n/a
Format
immunoaffinity purified
Size
600 μg
Concentration
3 mg/ml
Applications
WB, IF, IHC-P
Reviews / Ratings
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Description
Goat polyclonal antibody to HTT. Huntingtin is a protein linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. Reacts huntingtin protein, amino acids 85-200. The antibody recognizes wild type and mutant huntingtin.
Immunogen
Purified recombinant peptide derived from within residues 85 to 200 aa of human HTT produced in E. coli
1. Miniarikova J, Zimmer V, Martier R, et al. Gene Ther. 2017 Oct. PMID:28771234, 2. Meunier C, Merienne N, Jolle C, et al. Glia. 2016 Jul. PMID: 27442486, 3. Deglon N, Merienne N, Genome editing for the treatment of huntington's disease, EP 2982758 A1 Patent, 2014