human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Isotype
n/a
Format
immunoaffinity purified
Size
300 μg
Concentration
3 mg/ml
Applications
WB
Reviews / Ratings
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Description
Goat polyclonal antibody to insulin receptor. INSR is a receptor tyrosine kinase. Preprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. The insulin signalling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein is activated by the binding of insulin or other ligands to this receptor. Using liver, HeLa and Skov3 cell lysates detects a 180 kDa band by Western blot.
Immunogen
Purified recombinant peptide within residues 1310 aa to the C-terminus of human INSR produced in E. coli.