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Description
RABBIT ANTI HUMAN PARKIN (pSer101). This item specifically recognises the 52kDa parkin protein, when phosphorylated at Ser101.Parkin is an E3 ubiquitin ligase highly expressed in the brain, which functions in the ubiquitin-proteasome system, together with the E2 ubiquitin conjugating co-enzyme UbcH7. Mutations in the parkin gene are associated with the hereditary neurodegenerative disorder known as autosomal recessive early onset Parkinson disease 2 (PARK2)/autosomal recessive juvenile
Immunogen
Synthetic phosphopeptide corresponding to an amino acid sequence within parkin, which includes phosphorylated Ser101.
Other Names
E3 ubiquitin-protein ligase parkin isoform 1; E3 ubiquitin-protein ligase parkin; E3 ubiquitin-protein ligase parkin; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson juvenile disease protein 2; parkinson protein 2, E3 ubiquitin protein ligase (parkin); parkin RBR E3 ubiquitin protein ligase; Parkinson juvenile disease protein 2; Parkinson disease protein 2, PARK2; PARK2; PDJ; PRKN; AR-JP; LPRS2; PRKN; Parkinson disease protein 2