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Description
Anti-Phospho-Ser378 Parkin. Specificity: Specific for the ~52k parkin protein phosphorylated at Ser378. Immunolabeling of the parkin band is absent in parkin S378 mutants.
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 conjugated to KLH Immunogen Species: Human
Other Names
E3 ubiquitin-protein ligase parkin isoform 1; E3 ubiquitin-protein ligase parkin; E3 ubiquitin-protein ligase parkin; parkinson juvenile disease protein 2; parkinson protein 2, E3 ubiquitin protein ligase (parkin); Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkin RBR E3 ubiquitin protein ligase; Parkinson juvenile disease protein 2, PARK2; PARK2; PDJ; PRKN; AR-JP; LPRS2; PRKN; Parkinson disease protein 2
? Jenner P, Dexter DT, Sian J, Schapira AH, Marsden CD (1992) Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann Neurol. 32 Suppl: S82-7. ? Yamamoto A, Friedlein A, Imai Y, Takahashi R, Kahle PJ, Haass C (2005) Parkin phosphorylation and modulation of its E# ubiquitin ligase activity. J Biol chem. 280(5):3390-9