Purity >95% by HPLC. Peptide antibiotic. Induces root curvature and malformation in plants. Antibacterial, antimalarial and antitrypanosomal. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents.
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Other Names
(-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-], 5-L-Leucine-Malformin A, BRN 4896114